Over the past 110 years, 61 girls and 283 130 boys have been named Isaac. The name Isaac ranks 9967th in the United States among the most common names for girls. For the first time more than ten times newborns were named Isaac in 1978. The peak of popularity of the name Isaac came in the 1990s and 2000s. You can see absolute numbers and relative numbers on the chart. Indicators per 100K more accurately assess the popularity of the name.