Over the past 110 years, 283 130 boys and 61 girls have been named Isaac. The name Isaac ranks 116th in the United States among the most common names for boys. For the first time more than ten times newborns were named Isaac in 1910. The peak of popularity of the name Isaac came in the 2000s and 2010s. You can see absolute numbers and relative numbers on the chart. Indicators per 100K more accurately assess the popularity of the name.