Over the past 110 years, 308 437 girls and 51 boys have been named Irene. The name Irene ranks 115th in the United States among the most common names for girls. For the first time more than ten times newborns were named Irene in 1910. The peak of popularity of the name Irene came in the 1910s and 1920s. You can see absolute numbers and relative numbers on the chart. Indicators per 100K more accurately assess the popularity of the name.